PhoB says she's still living her fondest memory; so am I.
Hardly "the first time MetaFilter clicked" for me, but here's how it changed my life.
I recognized scrump as a neighbor from this thread, but I hadn't met him when he posted this inaugural MeJob. Despite scrump's threat? promise? that he'd "read your posting history on MeFi if you contact me, and it will, for better or worse, form part of my impression of you as a candidate," I got the job.
Four and a half years later I'm still there and it's still the best job I've ever had. I look forward to going to work every day, which I guess is hardly surprising given that I actually get to work with mefites.